Exploring alternatives to Prelone can provide patients with options that suit various health conditions and preferences. Dexamethasone serves as a potent substitution while natural options like Turmeric and Ginger offer anti-inflammatory benefits. Methotrexate and Mercaptopurine help in reducing steroid dependency, and Palmitoylethanolamide (PEA) and Quercetin offer natural relief. Each alternative presents different pros and cons, making it crucial to consult healthcare providers for suitable recommendations.